Bioequivalence and Bioavailability Forum

Highly variable drug product [PK / PD]

posted by jag009  – NJ, 2013-02-05 23:03 (4893 d 06:51 ago) – Posting: # 9968
Views: 11,387

Hi all,

Based on your experience , how often does one encounter a highly variable drug product "Test" --> Meaning the intrasubject CV of the test product being much higher than that of the reference product. The reference product itself is already highly variable (>30%).

Thanks
John

Complete thread:

• Highly variable drug productjag009 2013-02-05 22:03 
  • Highly variable drug product drgunasakaran1 2013-02-06 08:31
    • Highly variable drug product jag009 2013-02-06 15:14
  • Highly variable drug product Dr_Dan 2013-02-06 12:10
    • Highly variable drug product jag009 2013-02-06 15:26
  • Highly variable drug product luvblooms 2013-02-06 12:27
    • Highly variable drug product jag009 2013-02-06 15:28
      • Highly variable drug product Dr_Dan 2013-02-07 11:00
        • HVD ≠ HVDP Helmut 2013-02-07 13:22
        • Highly variable drug product jag009 2013-02-07 15:22