Log in
RegisterBE # dose proportionality [PK / PD]
posted by Helmut 
– Vienna, Austria, 2010-08-28 16:29 (5369 d 10:34 ago) – Posting: # 5863
Views: 5,848
Dear Cmax!
BE studies (test vs. reference at the same dose level) are not suitable to assess dose proportionality. I have occasionally seen 4-way cross-over studies (three dose levels of test vs. one dose level of reference).
So what?
❝ if i have a BE study from that how we can make it out is it follows non linear kinetic...
BE studies (test vs. reference at the same dose level) are not suitable to assess dose proportionality. I have occasionally seen 4-way cross-over studies (three dose levels of test vs. one dose level of reference).
❝ if you search in internet few works shows it follows non linear PK...
So what?
—
Dif-tor heh smusma 🖖🏼 Довге життя Україна!![[image]](https://static.bebac.at/pics/Blue_and_yellow_ribbon_UA.png)
Helmut Schütz
![[image]](https://static.bebac.at/img/CC by.png)
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Complete thread:
- Non Linearity Cmax 2010-08-13 18:12
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Non Linearity ElMaestro 2010-08-13 18:31
- Non Linearity (SD vs. MD) Helmut 2010-08-13 19:11
- Non Linearity (SD vs. MD) Cmax 2010-08-27 20:04
- BE # dose proportionalityHelmut 2010-08-28 14:29
- Non Linearity (SD vs. MD) Cmax 2010-08-27 20:04
- Non Linearity (SD vs. MD) Helmut 2010-08-13 19:11
- Non Linearity ElMaestro 2010-08-13 18:31
Ing. Helmut Schütz