calculating BE with minimum of data [PK / PD]

posted by Aceto81 – Belgium, 2008-07-17 14:25 (6140 d 23:45 ago) – Posting: # 2051
Views: 6,720

Hello,

I've been following this forum now for a few months, but I'm really new in the field of PK/PD.
I would like to know if it's possible to calculate the bioequivalence while only having the concentrations and %RSD.
I have found some threads on this forum like this link, but they all start with all the subjects used, not with the %RSD.

Here is an example:

Prep   Time     conc    %RSD
A       0.5     931.3   23.7
A       1      4051     19.5
A       2      4188.3   17.2
A       4      1258.7   25.5
A       8       305.7   21.9
A      12       151.6   26.1
A      24        93.3   22.4
B       0.5     851.6   20.2
B       1      3826.6   15.8
B       2      4135.5   21.6
B       4      1211.7   19.2
B       8       323.8   19.9
B      12       162.2   20.6
B      24        98.2   18.6



Kind regards

Ace

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