Bioequivalence and Bioavailability Forum • Cmax value higher than AUC

Cmax value higher than AUC [PK / PD]

posted by ElMaestro – Denmark, 2015-02-16 15:01 (4148 d 00:52 ago) – Posting: # 14432
Views: 17,748

Hi msnaimar,

❝ For eg., obtained Cmax is 1000ng/mL and AUCt is 730ng8h/mL. I suspect this particular observations may due to data set error. However, I don't have raw data to verify this results, thus need expertise opinion.

It doesn't make sense. At least not to me.
AUCt is a concentration integrated over time, Cmax is a concentration.

John has two shirts. One is green, the other one cost him $80. Which one is warmer?

—
Pass or fail!
ElMaestro

Complete thread:

Cmax value higher than AUC msmnainar 2015-02-16 13:41
- Cmax value higher than AUC ElMaestro 2015-02-16 13:46
  - Cmax value higher than AUC msmnainar 2015-02-16 13:51
    - Cmax value higher than AUCElMaestro 2015-02-16 14:01
      - Cmax value higher than AUC nobody 2015-02-16 14:23
      - Cmax value higher than AUC Dr_Dan 2015-02-17 08:11
        
        Cmax value higher than AUC nobody 2015-02-17 09:38
        
        Cmax value higher than AUC janmacek 2015-02-17 10:41
        
        Cmax value higher than AUC nobody 2015-02-17 11:19
        
        Cmax value higher than AUC msmnainar 2015-02-17 11:36
        
        Magic ElMaestrolophystic RoadShow ElMaestro 2015-02-17 14:56
        
        Magic ElMaestrolophystic RoadShow janmacek 2015-02-17 16:02
        
        Magic ElMaestrolophystic RoadShow nobody 2015-02-17 16:32
        Bizarre discussion… Helmut 2015-02-17 17:06
        
        Bizarre discussion… janmacek 2015-02-17 17:42
        
        Cmax value higher than AUC Dr_Dan 2015-02-17 18:53
        
        Cmax value higher than AUC nobody 2015-02-17 20:16