Bioequivalence and Bioavailability Forum • optimal individualized PK sampling time points

optimal individualized PK sampling time points [PK / PD]

posted by martin – Austria, 2015-02-14 11:51 (4142 d 12:13 ago) – Posting: # 14423
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Dear all,

I wonder if somebody has experience in defining optimal individualized sampling time points based on an available PopPK model.

PopPK model is available providing a predicted PK-curve for a given subject based on his/her covariates
These curves can differ heavily between subjects (based on their covariates)
For this reason, I think an optimal individualized PK-sampling scheme for a given subject might be useful.

Any ideas and suggestions (e.g. literature) are highly appreciated

Best regards

Martin

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optimal individualized PK sampling time pointsmartin 2015-02-14 10:51

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