Bioequivalence and Bioavailability Forum • post additional studies

post additional studies [PK / PD]

posted by ElMaestro – Denmark, 2015-01-13 18:46 (4174 d 22:41 ago) – Posting: # 14284
Views: 11,500

Hi Nobody,

❝ Maybe we should collect some data to support the nonsense-theory for this parameter? :-)

❝

❝ I will post here additional studies as I find them...

Excellent idea.
Let's see the numbers. In particular, what sample size is necessary to prove BE for a drug against itself if we look at Ctrough? Once calculate please tell me what level of confidence would that sample size give us for AUCt and Cmax?

Would be great to get some insight.

—
Pass or fail!
ElMaestro

Complete thread:

Lottery or science? nobody 2015-01-13 10:21
- Lottery or science? ElMaestro 2015-01-13 10:38
  - Lottery or science? nobody 2015-01-13 10:45
    - Lottery or science? ElMaestro 2015-01-13 11:05
      - Lottery or science? nobody 2015-01-13 11:23
        
        Lottery: maybe. Science: no. Helmut 2015-01-13 13:50
        
        Lottery: maybe. Science: occasionally ElMaestro 2015-01-13 16:45
        
        Lottery: maybe. Science: occasionally nobody 2015-01-13 17:16
        
        Lottery: maybe. Science: no. nobody 2015-01-13 17:12
        
        post additional studiesElMaestro 2015-01-13 17:46
        
        post additional studies nobody 2015-01-13 18:28
        
        Historic abstract of Cmin in BE Helmut 2015-01-14 01:42
        
        Historic abstract of Cmin in BE nobody 2015-01-14 08:42