Lottery or science? [PK / PD]

posted by nobody – 2015-01-13 11:45 (3770 d 03:24 ago) – Posting: # 14277
Views: 9,423

Yepp, it was bioequivalent. But is this a merrit of the formulation? Or was it purely by chance (if you have a look at the lower limit of the CI for Ctrough)? Or was it something else ;-)?

Imagine that a slightly different trough value for ONE formulation in a SINGLE volunteer might have resulted in a lower limit of CI for Ctrough of 79.98%

Getting clearer now?

Kindest regards, nobody

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