Bioequivalence and Bioavailability Forum

PK simulation [🇷 for BE/BA]

posted by jag009  – NJ, 2012-03-30 22:34 (5203 d 10:32 ago) – Posting: # 8359
Views: 15,955

Hi Helmut,

❝   V      <- rlnorm(n=1, meanlog=log(V.d)-0.5*log(V.c^2+1),

❝               sdlog=sqrt(log(V.c^2+1)))

❝   k01    <- rlnorm(n=1, meanlog=log(k01.d)-0.5*log(k01.c^2+1),

❝               sdlog=sqrt(log(k01.c^2+1)))

Sorry for the interruption and excuse me for my novice question... How did you arrive at the meanlog equation? I looked the rlnorm syntax from R manual and the mean equation different.

Thanks

John

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Hi Helmut,
Never mind.. It's Friday here. Wasn't thinking straight...

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Edit: Copypasted from follow-up post. You can edit your posts for 24 hours. [Helmut]
P.S.: See Martin’s post.

Complete thread:

• PK simulation Helmut 2012-03-29 18:52 
  • PK simulation d_labes 2012-03-30 15:38
    • PK simulation Helmut 2012-03-30 15:56
      • PK simulation - log-normal d_labes 2012-03-31 14:40
    • Why all this fuzz? Helmut 2012-03-30 18:46
  • PK simulationjag009 2012-03-30 20:34
  • PK simulation jag009 2012-04-04 17:03
    • R function rlnorm() d_labes 2012-04-05 09:15
    • Lognormal vs. truncated normal Helmut 2012-04-05 14:27
      • Lognormal vs. truncated normal jag009 2012-04-05 17:52