Bioequivalence and Bioavailability Forum • Never eaten Cadmium deliberately

Never eaten Cadmium deliberately [🇷 for BE/BA]

posted by Helmut – Vienna, Austria, 2011-01-20 16:25 (5264 d 16:36 ago) – Posting: # 6457
Views: 30,949

Dear D. Labes!

❝ Lets see what happens with this approach:

❝ require(PowerTOST)

0-8.3

expected
interesting
strange

❝ Moreover the classical power formulas have nowhere the scABE constraint

❝ "point est. must be within 0.8-1.25" as presupposition.

We can't incoporate a political constraint in an explicit statistical formula. The only way IMHO would be to go with Monte Carlo simulations.

Power: That which is wielded by the priesthood of clinical trials, the statisticians,
and a stick which they use to beta their colleagues.
Stephen Senn (Statistical Issues in Drug Development, Wiley p171, 2004)

P.S.: Added one missing '}' to your code above.

—
Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

Feature suggestion for bear and PowerTOST ElMaestro 2011-01-16 19:13
- Sample size for widened scaled ABE limits d_labes 2011-01-17 13:19
  - 0.760 or... Helmut 2011-01-17 14:38
    - ... full precision is the question d_labes 2011-01-17 16:37
      - ... full precision is the question Helmut 2011-01-17 18:06
        
        OT: Number of horns on a unicorn d_labes 2011-01-18 08:32
        
        Goooogle Helmut 2011-01-18 11:44
  - Cadmium ElMaestro 2011-01-19 17:50
    - Never eaten Cadmium deliberately d_labes 2011-01-20 15:00
      - Never eaten Cadmium deliberatelyHelmut 2011-01-20 15:25
        
        Call of duty for simulants d_labes 2011-01-20 16:15
        
        Counterinuitive Helmut 2011-01-21 04:13
        
        Counterintuitive d_labes 2011-01-21 08:36
        
        Counterintuitive Helmut 2011-01-21 12:53
        
        Counterinuitive, but ... d_labes 2011-01-21 12:12
        
        Counterinuitive, but ... Helmut 2011-01-21 13:01
        
        Wow, Wow ... d_labes 2011-01-21 14:43
        
        Never eaten Cadmium deliberately ElMaestro 2011-01-21 12:59
        
        Simulants of the world, unite! Helmut 2011-01-21 14:05
        
        Simulants of the world, unite! ElMaestro 2011-01-21 14:52
        
        Hyslop, Howe, scaled ABE and that all d_labes 2011-01-21 15:28
        
        Hyslop, Howe, scaled ABE and that all ElMaestro 2011-01-21 15:45
        
        scABE and missings d_labes 2011-01-21 16:19
        
        Intuition Helmut 2011-01-21 18:41
      - Never eaten Cadmium deliberately ElMaestro 2011-01-20 15:34
        
        Use of Cadmium d_labes 2011-01-20 16:06
        
        Use of Cadmium ElMaestro 2011-01-20 16:52
        Use of Cadmium ElMaestro 2011-01-20 17:53