Trapezoidal rule - PK [🇷 for BE/BA]

posted by Helmut Homepage – Vienna, Austria, 2010-04-20 14:53 (5541 d 05:56 ago) – Posting: # 5173
Views: 8,748

Dear D. Labes,

another option (besides bear, of course) in package PK by Thomas Jaki and Martin J. Wolfsegger:

time <- c(0,0.25,0.5,0.75,1,1.5,2,2.5,3,4,5,6)
conc <- c(0,5.67,20.6,28.7,22.5,17.4,17.7,13.4,11.0,8.23,5.14,2.84)
auc(conc,time,design='complete')


gives

Estimation for a complete data design

                  AUC     AUMC
observed     69.47000 156.1381
interpolated       NA       NA
infinity     74.80844 198.2036

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