Bioequivalence and Bioavailability Forum • Let's skip the fancy nesting syntax!

Let's skip the fancy nesting syntax! [🇷 for BE/BA]

posted by yjlee168 – Kaohsiung, Taiwan, 2009-08-28 00:26 (5777 d 14:01 ago) – Posting: # 4129
Views: 13,510

Dear EM,

❝ [...] Nesting in a model matrix is the same as interactions. This is why we get same results if we use "lnAuc ~ Subj : Seq + Seq + Per + Trt". However,[...]

What if we keep same data matrix as before (e.g., as in bear), but change the model with "lnAUC ~ (1|Subj:Seq) + Seq + Per + Trt"? I haven't tried it yet. I read this from the text: Faraway JJ, Extending the Linear Model with R - Generalized Linear, Mixed Effects and Nonparametric Regression Models. Chapman & Hall/CRC, 2006. It seems that we will get normal "Subj: Seq" in anova table in this case.

—
All the best,
-- Yung-jin Lee
bear v2.9.2:- created by Hsin-ya Lee & Yung-jin Lee
Kaohsiung, Taiwan https://www.pkpd168.com/bear
Download link (updated) -> here

Complete thread:

Let's skip the fancy nesting syntax! ElMaestro 2009-08-26 20:54
- Let's skip the fancy nesting syntax! yjlee168 2009-08-26 22:29
  - Let's skip the fancy nesting syntax! ElMaestro 2009-08-26 22:46
    - Let's skip the fancy nesting syntax! yjlee168 2009-08-27 20:54
      - Let's skip the fancy nesting syntax! ElMaestro 2009-08-27 22:14
- Let's skip the fancy nesting syntax!yjlee168 2009-08-27 22:26
  - Let's skip the fancy nesting syntax! ElMaestro 2009-08-27 22:46
  - Simple solution ElMaestro 2009-08-27 23:53
    - Simple solution yjlee168 2009-09-07 01:53
      - Type III SS again ElMaestro 2009-09-07 15:47
        
        Type III SS again yjlee168 2009-09-07 18:08
        
        Type III SS again ElMaestro 2009-09-07 19:53