Bioequivalence and Bioavailability Forum • Mean as intercept; model matrices

Mean as intercept; model matrices [🇷 for BE/BA]

posted by yjlee168 – Kaohsiung, Taiwan, 2009-05-21 15:35 (5875 d 01:05 ago) – Posting: # 3721
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dear Elmaestro,

So far we still cannot figure out why the intercept is not the mean of lnY. However, you put Subj as one of regressors in your lm() functions. In Chow & Liu's model, the S(i,k) is the intersubject residuals of Subj i on Sequence k, not Subj itself. Could this be the reason that these two models might be different? What we use in bear with your example is like the following:
Snot <- lm(lnY~Trt+Subj:Seq+Per+Seq) for a 2x2x2 ABE. It works o.k..

❝ Snot = lm(lnY~Trt+Subj+Seq+Per) ## seems to be standard syntax in

❝ 1. Chow & Liu's model specification is

❝ lnY = Mean + S(i,k) + P(j) + F(j,k) + C(j-1,k) + E(i,j,k)

—
All the best,
-- Yung-jin Lee
bear v2.9.2:- created by Hsin-ya Lee & Yung-jin Lee
Kaohsiung, Taiwan https://www.pkpd168.com/bear
Download link (updated) -> here

Complete thread:

Mean as intercept; model matrices ElMaestro 2009-05-20 20:35
- Mean as intercept; model matricesyjlee168 2009-05-21 13:35
  - Mean as intercept; model matrices ElMaestro 2009-05-21 14:30
- Mean as intercept; model matrices ElMaestro 2009-05-22 14:39
  - Mean as intercept; model matrices yjlee168 2009-05-23 20:06
  - Mean as intercept; model matrices Aceto81 2009-05-26 10:28
- Mean as intercept; model matrices yjlee168 2009-05-23 19:30
  - Mean as intercept; model matrices ElMaestro 2009-05-23 19:53
- Reparameterization d_labes 2009-05-25 11:47
  - Reparameterization yjlee168 2009-05-25 14:17
  - Reparameterization ElMaestro 2009-05-25 20:29
    - Reparameterized brain d_labes 2009-05-26 08:01