Bioequivalence and Bioavailability Forum • AUC in Bear

AUC in Bear [🇷 for BE/BA]

posted by d_labes – Berlin, Germany, 2008-12-15 16:19 (6032 d 09:48 ago) – Posting: # 2926
Views: 11,899

Dear Rusers, dear Bear inventors, dear all,

after looking at the details of NCA analysis in Bear (see NCA_PK.txt) I wonder, if/why the time point zero is not included in the AUC(0-tlast) calculations.

Any reasons for that, if really not included?
Is this not an 'oral' application dataset?

Further question: What about missing values at t=0.25 h (f.i. subject 2, 4 ...) for the built-in dataset. Missing or <LLOQ?

—
Regards,

Detlew

Complete thread:

AUC in Beard_labes 2008-12-15 15:19
- AUC in Bear yjlee168 2008-12-17 18:57
  - Degenerated trapezoid ;-) d_labes 2008-12-18 08:25
    - Degenerated trapezoid ;-) yjlee168 2008-12-18 08:44
      - Bear at Home d_labes 2008-12-18 09:02
        
        Bear at Home yjlee168 2008-12-18 09:47
        
        Bear - statistical summary d_labes 2008-12-18 11:46
        
        Bear - statistical summary yjlee168 2008-12-18 12:13