Bioequivalence and Bioavailability Forum • update: bear v1.1.4 for R (a free tool for ABE)

update: bear v1.1.4 for R (a free tool for ABE) [🇷 for BE/BA]

posted by yjlee168 – Kaohsiung, Taiwan, 2008-09-17 15:33 (6484 d 19:40 ago) – Posting: # 2372
Views: 29,937
(edited on 2008-09-17 19:32)

Dear all,

It's been a while since we released bear v1.0.0 at this forum on last July. Then we have received lots of comments from bear's users, also including very nice experts at this forum. Though I tried to update some change log of bear since v1.0.0, I had problem to log in this forum from time to time. Then we went to Dortmund, Germany, for the R Annual Meeting (userR!2008) during August 9 to 18. A very nice meeting there. The following are the change log and Todo lists since v1.0.0.

Change Log (Sept. 17, 2008)
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v1.1.4

fixed the compatibility for iMac and Linux (thanks to Koji Shimamoto, Tokyo, Japan; also for testing bear on iMac machine)

v1.1.3-1.1.0

removed the function of "Sample size estimation (raw data)"; also improve the function of "Sample size estimation (Log Transform)."
fixed the rounding error in the display of "Sample size estimation (Log transform)" (thanks to Helmut)
fixed some the format (comma, semicolon, etc.) of import data file (thanks to Helmut); users now can choose their favorite formats.
display the PATH where bear will import from and will output all results to.
display only one graphic devices (using PageDown & PageUp to change plots) (thanks to Helmut)
display semilog (not linear) plots when choosing data points to do linear regression for lambda_z (kel) in NCA (thanks to Helmut)
calculate CV_intra & CV_inter now (thanks to Helmut)
output both the .csv and the .RData file formats obtained from NCA; users can choose either one for anova.
use "Tests of SUBJECT(SEQUENCE) as an error term" in ANOVA output (thanks to Helmut)
changed ANOVA(GLM) to ANOVA (lm) in the menu title (thanks to EIMaestro)

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Todo Lists (Sept. 17, 2008)
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calculate intra-subject residuals (a little bit tough...) (suggested by Helmut)
implement the better algorithm for lambda_z calculation (suggested by martin and Ace; especially Ace who provided us his R codes for this) as additional options
implement "lme" for ANOVA as the additional method to current "lm". (suggested by EIMaestro)
implement the "Save" function for data points selection for each subjects before doing NCA (using data.frame()?)
add Type III SS (this should be able to be done quickly...)
add methods for replicated study... (it may take longer for this).

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—
All the best,
-- Yung-jin Lee
bear v2.9.6:- created by Hsin-ya Lee & Yung-jin Lee
Kaohsiung, Taiwan https://www.pkpd168.com/bear
Download link (updated) -> here

Complete thread:

update: bear v1.1.4 for R (a free tool for ABE)yjlee168 2008-09-17 13:33
- update: bear v1.1.4 for R (a free tool for ABE) Helmut 2008-09-17 16:59
  - update: bear v1.1.4 for R (a free tool for ABE) yjlee168 2008-09-17 21:03
- update: bear v1.1.4 for R (a free tool for ABE) martin 2008-09-19 13:13
  - update: bear v1.1.4 for R (a free tool for ABE) yjlee168 2008-09-22 18:19
  - update: bear v1.1.4 for R (a free tool for ABE) Helmut 2008-09-23 00:46
    - update: bear v1.1.4 for R (a free tool for ABE) martin 2008-09-27 09:37
      - Package lee for R Helmut 2008-09-27 14:05
  - update: bear v1.1.4 for R (a free tool for ABE) yjlee168 2008-09-23 10:07
    - update: bear v1.1.4 for R (a free tool for ABE) martin 2008-09-27 09:25
      - update: bear v1.1.4 for R (a free tool for ABE) yjlee168 2008-09-29 12:03
        
        update: bear v1.1.4 for R (a free tool for ABE) Helmut 2008-09-29 12:10
        
        update: bear v1.1.4 for R (a free tool for ABE) yjlee168 2008-09-29 13:07
        
        modified function for selection of time points martin 2008-10-11 15:30
        
        modified function for selection of time points yjlee168 2008-10-11 19:45
        
        last 3 time points martin 2008-10-12 00:04
        
        modified function for selection of time points yjlee168 2008-10-16 11:20
        
        modified function for selection of time points Aceto81 2008-10-16 12:09
        
        modified code martin 2008-10-16 12:29
        
        modified code Aceto81 2008-10-16 14:11
        
        abs(AIC) martin 2008-10-16 15:03
        example martin 2008-10-16 20:02
        
        example Aceto81 2008-10-17 12:30