PKNCA Package usage [🇷 for BE/BA]

posted by yjlee168 Homepage – Kaohsiung, Taiwan, 2019-11-20 15:35 (2038 d 01:11 ago) – Posting: # 20840
Views: 7,398

Hi sury

❝ ...

❝ And i have tried to estimate the PK parameters using BEAR package. but it is not getting the same results as that of the WinNonlin


Which method did you use for AUC calculation with bear? 'linear-up/log-down' or 'all linear' trapezoidal method? The default method in bear is 'linear-up/log-down'. The other issue to cause the difference is the method used to estimate lambda z.

All the best,
-- Yung-jin Lee
bear v2.9.2:- created by Hsin-ya Lee & Yung-jin Lee
Kaohsiung, Taiwan https://www.pkpd168.com/bear
Download link (updated) -> here

Complete thread:

UA Flag
Activity
 Admin contact
23,424 posts in 4,927 threads, 1,677 registered users;
37 visitors (0 registered, 37 guests [including 9 identified bots]).
Forum time: 17:46 CEST (Europe/Vienna)

Philosophy, like medicine, has plenty of drugs, few good remedies,
and hardly any specific cures.    Sebastien-Roch Nicolas de Chamfort

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5