Bioequivalence and Bioavailability Forum • Previously data point selection for lambda z estimate issue in bear

Previously data point selection for lambda z estimate issue in bear [🇷 for BE/BA]

posted by yjlee168 – Kaohsiung, Taiwan, 2019-11-20 15:07 (2401 d 23:30 ago) – Posting: # 20839
Views: 11,155

Hi Kirill,

Thanks for posting the issue here. Th term 'previously data point selection for lambda z' is kind of confusing. Here it means only for previously manual selection data point, not for ARS, AIC, TTT or any others. The default file name for 'previously manual data point selection for lambda z' is '***_lambda_z_manual_select_all.RData'

❝ when I tried to use dataset with previously selected points,

❝ it seems that bear is trying to find columns:

❝ "subj" "time" "conc" "conc_data" "drug"

That's correct. This is the exact data format for 'previously manual data point selection for lambda z'. You have to select 'manual selection' under 'data point selection for lambda z estimate'. Then you will get this file (***_lambda_z_manual_select_all.RData) in your working directory.

❝ ...

❝ but ***_lambda_z_select_all.RData contains:

❝ "subj" "seq" "prd" "drug" "time" "conc"

This is correct too. However, this file is just a part of NCA outputs in bear. It is absolutely not the 'previously manual data point selection for lambda z'.

Hope this can help.

—
All the best,
-- Yung-jin Lee
bear v2.9.6:- created by Hsin-ya Lee & Yung-jin Lee
Kaohsiung, Taiwan https://www.pkpd168.com/bear
Download link (updated) -> here

Complete thread:

Previously data point selection for lambda z estimate issue in bear kvoronov 2019-11-20 10:55
- Previously data point selection for lambda z estimate issue in bearyjlee168 2019-11-20 14:07
  - Previously data point selection for lambda z estimate issue in bear kvoronov 2019-11-20 15:40
    - combine ARS & manual selection for lambda z in bear yjlee168 2019-11-20 17:12
      - Automatic → visual inspection/adjustment Helmut 2019-11-20 17:32
        
        Automatic → visual inspection/adjustment yjlee168 2019-11-20 18:48
        
        Automatic → visual inspection/adjustment Helmut 2019-11-20 18:59
        
        Automatic → visual inspection/adjustment yjlee168 2019-11-20 21:05
        
        OT for nerds Helmut 2019-11-21 00:53
      - combine ARS & manual selection for lambda z in bear kvoronov 2019-11-21 21:57
        
        combine ARS & manual selection for lambda z in bear yjlee168 2019-11-21 22:15
        
        combine ARS & manual selection for lambda z in bear kvoronov 2019-11-22 13:57
        
        bear v2.8.7 is released. yjlee168 2019-11-22 20:48
        
        bear v2.8.7 is released. kvoronov 2019-11-25 18:14
        
        auto switch from ARS to manual selection yjlee168 2019-11-25 20:46
        
        auto switch from ARS to manual selection kvoronov 2019-11-28 14:19