Bioequivalence and Bioavailability Forum

Hi GM,

not Detlew but answering anyway.

❝ I am trying to calculate the sample size for replicate design using R software with sampleN.RSABE.

So why are you not simply using it?

library(PowerTOST)
sampleN.RSABE(CV=0.4, theta0=0.9, targetpower=0.8, design="2x2x4")

If you want further information about the arguments and their defaults, type ?sampleN.RSABE in the R-console / R-Studio’s console or consult the online manual.

❝ I am a beginner of R software

If you want to dive into the code, be aware of R’s steep learning curve.

❝ […] but I tried to understand this.

OK, this is a laudable.

❝ There are some intermediate functions like .sampleN0, .sampleN0.2, .power.RSABE are involved.

❝ I got the informationn of first two functions from the same github. but not the third one.

.power.RSABE is contained in power_RSABE2L_isc.R.