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Registerzero (0), missing (NA), or BLLOQ (0 or NA) in bear [🇷 for BE/BA]
Dear yjlee168,
i got almost the same error message with bear_2.7.5 on R3.2.3 for mac.
--- the list of problematic subject data ---
--------------------------------------------
-> the subj# 18 (Test) in sequence# 1, period# 2,
λz (kel) cannot be calculated with ARS or AIC..
-> the subj# 19 (Test) in sequence# 1, period# 2,
λz (kel) cannot be calculated with ARS or AIC..
is there any solution for it yet?
is there any option to work with these cases (2 subjects with error message) to calculate the parameter by manual selection of 2-6 point after Cmax?
Greetings.
Edit: formatted using BBCodes. Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post! [Ohlbe]
i got almost the same error message with bear_2.7.5 on R3.2.3 for mac.
--- the list of problematic subject data ---
--------------------------------------------
-> the subj# 18 (Test) in sequence# 1, period# 2,
λz (kel) cannot be calculated with ARS or AIC..
subj seq prd drug time conc
18 1 2 2 0.00 0.00
18 1 2 2 0.25 4.17
18 1 2 2 0.50 12.99
18 1 2 2 1.00 18.23
18 1 2 2 1.50 25.69
18 1 2 2 2.00 42.52
18 1 2 2 2.50 57.78
18 1 2 2 3.00 66.04
18 1 2 2 3.50 77.02
18 1 2 2 4.00 27.46
18 1 2 2 5.00 15.65
18 1 2 2 6.00 9.24
18 1 2 2 8.00 7.43
18 1 2 2 10.00 0.92
18 1 2 2 24.00 <NA>-> the subj# 19 (Test) in sequence# 1, period# 2,
λz (kel) cannot be calculated with ARS or AIC..
subj seq prd drug time conc
19 1 2 2 0.00 0.00
19 1 2 2 0.25 38.40
19 1 2 2 0.50 47.86
19 1 2 2 1.00 105.70
19 1 2 2 1.50 117.36
19 1 2 2 2.00 124.71
19 1 2 2 2.50 66.82
19 1 2 2 3.00 55.15
19 1 2 2 3.50 39.34
19 1 2 2 4.00 27.11
19 1 2 2 5.00 18.35
19 1 2 2 6.00 10.50
19 1 2 2 8.00 7.37
19 1 2 2 10.00 3.43
19 1 2 2 24.00 0.250763777is there any solution for it yet?
is there any option to work with these cases (2 subjects with error message) to calculate the parameter by manual selection of 2-6 point after Cmax?
Greetings.
Edit: formatted using BBCodes. Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post! [Ohlbe]
—
Mahmoud Teaima, PhD.
Mahmoud Teaima, PhD.
Complete thread:
- bear v2.7.0 released yjlee168 2015-12-07 09:18
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Suggestion ElMaestro 2015-12-07 10:12
- Suggestion yjlee168 2015-12-07 10:55
- Suggestion Helmut 2015-12-07 14:01
- Suggestion yjlee168 2015-12-07 18:51
- Suggestion Helmut 2015-12-07 14:01
- Suggestion yjlee168 2015-12-07 10:55
- bear v2.7.0 released Astea 2015-12-10 16:36
- if Clast is zero in bear yjlee168 2015-12-10 17:23
- if Clast is zero in bear Astea 2015-12-10 20:50
- if Clast is zero in bear yjlee168 2015-12-11 03:28
- if Clast is zero in bear Astea 2015-12-11 09:39
- if Clast is zero in bear yjlee168 2015-12-11 17:16
- if Clast is zero in bear Astea 2015-12-11 09:39
- if Clast is zero in bear yjlee168 2015-12-11 03:28
- bear v2.7.1 yjlee168 2015-12-15 10:21
- bear v2.7.1 Astea 2015-12-15 19:32
- BLLOQ ≠ 0 with measured drug plasma conc. yjlee168 2015-12-15 20:17
- BLLOQ ≠ 0 with measured drug plasma conc. Helmut 2015-12-16 01:45
- BLLOQ ≠ 0 with measured drug plasma conc. yjlee168 2015-12-16 11:38
- BLLOQ ≠ 0 ∀ t > 0 Helmut 2015-12-16 12:40
- BLLOQ ∋ { 0, ≈0, BLLOQ{...} ∀ t > 0} yjlee168 2015-12-16 18:22
- BLLOQ at first two time ponts, AUC calculation Astea 2016-01-30 17:11
- zero-zero with AUC calculation in bear yjlee168 2016-01-30 19:00
- BQL rules in bear mittyri 2016-02-01 22:16
- BQL rules in bear yjlee168 2016-02-02 10:59
- possible solutions? yjlee168 2016-02-02 21:30
- zero (0), missing (NA), or BLLOQ (0 or NA) in bear yjlee168 2016-02-03 09:04
- zero (0), missing (NA), or BLLOQ (0 or NA) in bearmahmoud-teaima 2016-02-08 21:28
- Please avoid Full Quotes (“TOFU”)! Ohlbe 2016-02-09 00:51
- error message in bear mahmoud-teaima 2016-02-09 04:55
- please check your dataset file yjlee168 2016-02-09 06:40
- please check your dataset file mahmoud-teaima 2016-02-09 15:00
- please check your dataset file yjlee168 2016-02-09 15:38
- please check your dataset file mahmoud-teaima 2016-02-09 15:00
- A possible R bug? yjlee168 2016-02-09 19:14
- Please avoid Full Quotes (“TOFU”)! Ohlbe 2016-02-09 00:51
- zero (0), missing (NA), or BLLOQ (0 or NA) in bearmahmoud-teaima 2016-02-08 21:28
- BQL rules in bear mittyri 2016-02-01 22:16
- zero-zero with AUC calculation in bear yjlee168 2016-01-30 19:00
- BLLOQ at first two time ponts, AUC calculation Astea 2016-01-30 17:11
- BLLOQ ∋ { 0, ≈0, BLLOQ{...} ∀ t > 0} yjlee168 2015-12-16 18:22
- BLLOQ ≠ 0 ∀ t > 0 Helmut 2015-12-16 12:40
- BLLOQ ≠ 0 with measured drug plasma conc. yjlee168 2015-12-16 11:38
- BLLOQ ≠ 0 with measured drug plasma conc. Helmut 2015-12-16 01:45
- BLLOQ ≠ 0 with measured drug plasma conc. yjlee168 2015-12-15 20:17
- bear v2.7.1 Astea 2015-12-15 19:32
- if Clast is zero in bear Astea 2015-12-10 20:50
- if Clast is zero in bear yjlee168 2015-12-10 17:23
- Suggestion ElMaestro 2015-12-07 10:12
Ing. Helmut Schütz