Bioequivalence and Bioavailability Forum

Dear BE-proff,

❝ As for statistic methods - sorry but I am not strong in them

Beware! Here you are on very slippery ground. Power calculation / sample size estimation are irresolvable connected to the statistical test methods you intend to use in the evaluation of your study results. The test (method) determines how the power hast to be calculated. It determines further the parameters necessary to do power calculations

Without an at least basic understanding of the statistics to use you can't IMHO do any reliable power calculation / sample size estimation. A cook book like approach as requested above doesn't work .

I highly recommend you the lectures/presentations Helmut has given on many places around the world. Especially those about sample size.
If you need some guidance how to use PowerTOST you may also search this forum. There are many discussions with that topic out there. Have a look f.i. into this post.