Bioequivalence and Bioavailability Forum • ANOVA F-test results and regulators

ANOVA F-test results and regulators [🇷 for BE/BA]

posted by d_labes – Berlin, Germany, 2015-06-12 17:44 (3661 d 10:50 ago) – Posting: # 14953
Views: 14,740

Huummmm,

❝ Why not just always fit the model with no intercept and type I. The first term is almost guaranteed to have a significant P-value. You can then discuss it as much as you feel like at the nuisance level. Specify Sequence first, and voila here's a nice discussion brewing already :-D You can have a standard answer ready for all procedures.

Didn't get your point. Can you elaborate in slow motion and simple words?

As I see it you can't discuss with regulators that their request is nuisance aka crap aka nonsense. Not if you have to discuss a submission.
Only if you meet one at conferences and have forgotten to take your pills ... :-D

—
Regards,

Detlew

Complete thread:

R code for lm.mod does not make sense dmfisher 2015-06-09 03:55
- R code for lm.mod does not make sense yjlee168 2015-06-09 17:57
  - R code for lm.mod does not make sense ElMaestro 2015-06-09 21:07
    - R code for lm.mod does not make sense yjlee168 2015-06-10 11:34
      - R code for lm.mod does not make sense ElMaestro 2015-06-10 14:22
        
        R code for lm.mod does not make sense yjlee168 2015-06-11 09:44
        
        Reference datasets Helmut 2015-06-11 11:50
        
        Reference datasets ElMaestro 2015-06-11 12:01
        
        Reference datasets yjlee168 2015-06-11 22:16
        Type III kuddel muddel d_labes 2015-06-12 09:04
        
        Type III kuddel muddel Helmut 2015-06-12 11:27
        
        ANOVA F-test results and regulators d_labes 2015-06-12 15:23
        
        ANOVA F-test results and regulators ElMaestro 2015-06-12 15:29
        
        ANOVA F-test results and regulatorsd_labes 2015-06-12 15:44
        
        ANOVA F-test results and regulators ElMaestro 2015-06-12 15:52
        
        Type III again ElMaestro 2015-06-12 12:18
        
        SAS OT d_labes 2015-06-12 15:32
        
        Reference datasets yjlee168 2015-06-11 19:56
        Test hypothesis of using Type I/III MS... yjlee168 2015-06-12 09:01
  - R code for lm.mod does not make sense dmfisher 2015-06-10 01:38