Bioequivalence and Bioavailability Forum

Dear userRs!

Yesterday I received an e-mail from the FDA’s CDER/OGD:
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</snip>

Well, I don’t. Given the numerous discussions we had about lme(), nlme:lme(), and lme4:lmer() it seems that it not possible to reproduce FDA’s SAS-code in R (df limbo). Something new from any of you?

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PS: Since Donald Schuirmann performed his simulations for NTID-scaling (RTRT|TRTR) in R, FDA should have some code, right?
PPS: Maybe the e-mail was triggered by this or that?

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Edit 2013-12-04: Quoted e-mail blacked out as requested by the FDA.