Tmax calculation [General Sta­tis­tics]

posted by VSL – India, 2012-08-26 23:17 (5045 d 21:51 ago) – Posting: # 9107
Views: 5,082

Dear All,
Please explore the following topics.
  1. In calculating descriptive statistics why Tmax is calculated as Median instead of Mean ?
  2. The time to maximum drug plasma concentration (Tmax) is examined but is not required to be within any specified limits. Why doesn't it require to prove Bioeuivalence on Tmax?
  3. If there is larger difference in Tmax between Test and Reference Formulation but not in Cmax,it would be rational comparison between T & R as for some therapeutic class drugs 'on set time of action' is more important?
Sincerely,
VSL

Edit: Category changed. [Helmut]

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