Tmax calculation [General Sta­tis­tics]

posted by VSL – India, 2012-08-26 23:17 (5040 d 15:57 ago) – Posting: # 9107
Views: 5,073

Dear All,
Please explore the following topics.
  1. In calculating descriptive statistics why Tmax is calculated as Median instead of Mean ?
  2. The time to maximum drug plasma concentration (Tmax) is examined but is not required to be within any specified limits. Why doesn't it require to prove Bioeuivalence on Tmax?
  3. If there is larger difference in Tmax between Test and Reference Formulation but not in Cmax,it would be rational comparison between T & R as for some therapeutic class drugs 'on set time of action' is more important?
Sincerely,
VSL

Edit: Category changed. [Helmut]

Complete thread:

UA Flag
Activity
 Admin contact
23,654 posts in 4,992 threads, 1,570 registered users;
116 visitors (0 registered, 116 guests [including 24 identified bots]).
Forum time: 15:15 CEST (Europe/Vienna)

The idea is to try and give all the information to help others
to judge the value of your contribution;
not just the information that leads to judgment
in one particular direction or another.    Richard Feynman

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5