Bioequivalence and Bioavailability Forum

maths versus understanding [General Statistics]

posted by msmnainar – India, 2012-06-25 12:59 (5103 d 03:16 ago) – Posting: # 8841
Views: 7,902

Dear ElMaestro

Thanks for your swift reply,

A plot of Ceq/(x/m) versus Ceq was depicted to obtain k1 and k2 values.
Ceq/(x/m) values are depicted for your ready reference.

Concentration   Ceq/(x/m)

                Product X

     1            0.5882

     2            0.5699

     3            0.5165

     4            0.6081

     5            1.0647

     6            1.4001

     7            2.4236

     8            3.3321

     9            5.4172

Regression analysis applied to yield a slope (a) and intercept (b) of the line.

The affinity constant, k 1, and capacity constant, k 2, are calculated from the slope and intercept as follows:

K1=a/b
K2=1/a

Here, actually we need to confirm whether the calculated steps/values are reproducible using back calculation.

Hope I am explained properly.

M. Sundar, India

—
Sundar. M

Complete thread:

Back calculation for QC purpose msmnainar 2012-06-24 09:06
- Back calculation for QC purpose ElMaestro 2012-06-24 11:12
  - Back calculation for QC purpose msmnainar 2012-06-25 05:12
  - Back calculation for QC purpose msmnainar 2012-06-25 08:46
    - maths versus understanding ElMaestro 2012-06-25 10:36
      - maths versus understandingmsmnainar 2012-06-25 10:59
        
        maths versus understanding ElMaestro 2012-06-25 11:03
        
        maths versus understanding msmnainar 2012-06-25 11:26
    - Back calculation for QC purpose ElMaestro 2012-06-25 11:35
      - Back calculation for QC purpose msmnainar 2012-06-25 12:00
        
        Back calculation for QC purpose ElMaestro 2012-06-25 13:19

maths versus understanding [General Sta­tis­tics]

Complete thread:

maths versus understanding [General Statistics]