Bioequivalence and Bioavailability Forum

Back calculation for QC purpose [General Statistics]

posted by ElMaestro – Denmark, 2012-06-24 13:12 (5104 d 03:08 ago) – Posting: # 8837
Views: 8,011

Hi msmnainar,

❝ Can anybody explain how to back calculate (formula captured below) to compare the results of phosphate binding capacity.

❝ Langmuir equation: Ceq/(x/m)=1/k1.k2+Ceq/k2

Do you mean isolating C_eq?

Let a=(x/m)

C/a=1/(k₁k₂)+(C/k₂)
<=>
C/a-C/k₂=1/(k₁k₂)
<=>
C(1/a-1/k₂)=1/(k₁k₂)
<=>
C=(1/(k₁k₂))/((1/a-1/k₂))
or
C=(1/(k₁k₂))/((1/(x/m)-1/k₂))

The latter can be re-arranged as necessary.

—
Pass or fail!
ElMaestro

Complete thread:

Back calculation for QC purpose msmnainar 2012-06-24 09:06
- Back calculation for QC purposeElMaestro 2012-06-24 11:12
  - Back calculation for QC purpose msmnainar 2012-06-25 05:12
  - Back calculation for QC purpose msmnainar 2012-06-25 08:46
    - maths versus understanding ElMaestro 2012-06-25 10:36
      - maths versus understanding msmnainar 2012-06-25 10:59
        
        maths versus understanding ElMaestro 2012-06-25 11:03
        
        maths versus understanding msmnainar 2012-06-25 11:26
    - Back calculation for QC purpose ElMaestro 2012-06-25 11:35
      - Back calculation for QC purpose msmnainar 2012-06-25 12:00
        
        Back calculation for QC purpose ElMaestro 2012-06-25 13:19

Back calculation for QC purpose [General Sta­tis­tics]

Complete thread:

Back calculation for QC purpose [General Statistics]