Bioequivalence and Bioavailability Forum

❝ Generally in statistics an alpha of 5% is considered appropriate. Whether this alpha level is appopriate or not is of course also a good question, but it has stuck for years and seems to be the tradition now.

Not in statistics but in parts of science/engineering where variability is so high that the risk of going for larger sample sizes is considered to give no further benefit. In industry 6σ is the buzzword. In the aerospace industry risk is often limited with 10^–5 (the best we currently can achieve in software development) + redundant systems which pushes the risk of failure to at least 1:10¹⁰.