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Dear d_labes,
yes, just like mandatory parametric evaluation of CI's even when residuals are non-normal. But we never do a parametric test when we don't know the distribution of residuals do we?
To be honest, I had no thought of your point at all when I wrote the post above. I guess one can argue that, there's probably both intra-row and intra-column correlation (same subject experiencing AEs in two or more categories for the same treatment, as well as same subject experiencing AE with test and ref respectively. There's always a whining subject with a ton of AEs, especially if the trial is in a Western country).
To HS: I had no idea Fisher's exact test could be done on tables larger than 2x2... This great forum is an eternal source of knowledge. Thank you for improving the statistic for Dr_Dan as well as extending my horizon.
❝ The statistics you do here is at least very approximative.
yes, just like mandatory parametric evaluation of CI's even when residuals are non-normal. But we never do a parametric test when we don't know the distribution of residuals do we?
To be honest, I had no thought of your point at all when I wrote the post above. I guess one can argue that, there's probably both intra-row and intra-column correlation (same subject experiencing AEs in two or more categories for the same treatment, as well as same subject experiencing AE with test and ref respectively. There's always a whining subject with a ton of AEs, especially if the trial is in a Western country).
To HS: I had no idea Fisher's exact test could be done on tables larger than 2x2... This great forum is an eternal source of knowledge. Thank you for improving the statistic for Dr_Dan as well as extending my horizon.
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Pass or fail!
ElMaestro
Pass or fail!
ElMaestro
Complete thread:
- Adverse events Dr_Dan 2011-09-01 11:27
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Significant differences in AEs Helmut 2011-09-01 12:18
- Significant differences in AEs Dr_Dan 2011-09-01 15:44
- Significant differences in AEs ElMaestro 2011-09-01 13:40
- Adverse events ElMaestro 2011-09-01 18:12
- Adverse events martin 2011-09-02 11:02
- Significant differences in AEs Helmut 2011-09-01 12:18
Ing. Helmut Schütz