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Registercriterion for TOST? [General Statistics]
posted by Helmut 
– Vienna, Austria, 2011-04-20 14:39 (5535 d 22:26 ago) – Posting: # 6928
Views: 4,507
Dear Yung-jin,
that’s weird. We perform a cross-over because generally CVintra < CVinter ⇒ less subjects are needed. There are (very few!) cases were CVintra > CVinter; in these cases a parallel design would be the better choice from an ethical point of view. TOST is independent from the design. Maybe the reviewer mixed up intra and inter? However, the applicability of TOST is independent from both the size of the CV(s) and the order (i.e., which one is larger).
that’s weird. We perform a cross-over because generally CVintra < CVinter ⇒ less subjects are needed. There are (very few!) cases were CVintra > CVinter; in these cases a parallel design would be the better choice from an ethical point of view. TOST is independent from the design. Maybe the reviewer mixed up intra and inter? However, the applicability of TOST is independent from both the size of the CV(s) and the order (i.e., which one is larger).
—
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Helmut Schütz
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Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Complete thread:
- criterion for TOST? yjlee168 2011-04-20 09:47
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- criterion for TOST? ElMaestro 2011-04-20 10:22
- criterion for TOST? yjlee168 2011-04-21 13:06
- criterion for TOST? ElMaestro 2011-04-21 13:18
- criterion for TOST? yjlee168 2011-04-21 13:06
- criterion for TOST?Helmut 2011-04-20 12:39
- criterion for TOST? ElMaestro 2011-04-20 10:22
Ing. Helmut Schütz