Statistical analysis of Cmax values < LOQ [General Sta­tis­tics]

posted by ElMaestro  – Denmark, 2010-10-01 19:53 (5736 d 02:54 ago) – Posting: # 5976
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Dear Ohlbe,

❝ Couldn't it happen in a first-in-man with ascending doses, in the lowest dose group ?


Yes, that sounds just about right and intuitive.
Would it perhaps even be possible to say it should only happen under those circumstances?
Yeah ok, at the time I am posting this we know it is an animal TK study, but disregarding this fact, I cannot think of any other situation where it could reasonably be expected to occur.

Pass or fail!
ElMaestro

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