Bioequivalence and Bioavailability Forum

Phoenix/WinNonlin-experts around? [General Sta­tis­tics]

posted by d_labes  – Berlin, Germany, 2010-07-13 14:15 (5827 d 06:36 ago) – Posting: # 5615
Views: 16,923

Dear Helmut!

❝ I got:

❝ Warning 11091: Newton's algorithm converged with modified Hessian.

❝ Output is suspect.

❝ Model may be over-specified. A simpler model could be tried.

❝ and sigma²_WR 0.1861995 (CV_WR 0.452397)

This is the continuation of our earlier discussion: The FDA model (and your specification is some sort of ) is over-specified for the extra-reference design.

Complete thread:

• SABE Reference Variability and CI Computation preyes323 2010-07-12 17:12 
  • Dataset Helmut 2010-07-12 17:26
    • Dataset preyes323 2010-07-12 18:20
      • Data format Helmut 2010-07-12 18:38
        • Data format preyes323 2010-07-13 01:16
          • SAS and/or Phoenix/WinNonlin-experts around? Helmut 2010-07-13 02:29
            • Phoenix/WinNonlin-experts around?d_labes 2010-07-13 12:15
              • Phoenix/WinNonlin-experts around? Helmut 2010-07-13 13:42
                • Mixed interest d_labes 2010-07-13 15:11
                  • Mixed interest Helmut 2010-07-13 19:19
                    • lme() answer and beyond ... d_labes 2010-07-14 10:41
                      • lme() answer and beyond ... Helmut 2010-07-14 13:47
                        • AIC, BIC and that all ... d_labes 2010-07-15 12:01
          • To Err is Human d_labes 2010-07-13 11:51
            • To Err is Human, but... Helmut 2010-07-13 13:45
              • ... to Arr is Pirate d_labes 2010-07-13 15:47
                • Brilliant page!!! ElMaestro 2010-07-14 21:03
            • To Err is Human preyes323 2010-07-14 14:45
              • Heads up! Helmut 2010-07-14 15:17
              • To Err is Teacher d_labes 2010-07-15 11:05
            • To Err is Human preyes323 2010-07-16 02:28
              • To Err is Human d_labes 2010-07-16 10:42
                • To Err is Human preyes323 2010-07-17 11:14
                  • Regulatory constants d_labes 2010-07-19 10:00
          • Data format ElMaestro 2011-02-06 11:54
            • SAS System Viewer Helmut 2011-02-06 13:02