Bioequivalence and Bioavailability Forum

Meta-analysis vs. naïve pooling [General Sta­tis­tics]

posted by Helmut  – Vienna, Austria, 2010-04-10 00:11 (5912 d 15:16 ago) – Posting: # 5072
Views: 10,594

Dear ElMaestro!

❝ Study will be a between-subject factor. Thus it should not influence the intra/residual. Adding "study" as a factor thus might not mean much in terms of the outcome as compared to an anova and the subsequent CI without that factor.

Right.

❝ Can you show a bit more?

Just leaving the office. Maybe next year.

❝ I wonder why the combined CV's (9.31%) are higher than those from the two individual studies.

Surprised me too.

❝ Were the subjects uniquely coded - i.e. "Subject 1" was uniquely assigned to either study 1 or 2 etc?

Yes. Codes were
study (1-2)
treatment (test/reference)
subject (001-013 in study 1, and 101-112 in study 2)
period (1-2)

P.S.: Nice signature.

—
Dif-tor heh smusma 🖖🏼 Довге життя Україна! 
Helmut Schütz


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Complete thread:

• Meta-analysis earlybird 2010-04-09 07:54 
  • Meta-analysis in SAS d_labes 2010-04-09 08:35
    • Meta-analysis vs. naïve pooling Helmut 2010-04-09 20:33
      • Meta-analysis vs. naïve pooling ElMaestro 2010-04-09 22:02
        • Meta-analysis vs. naïve poolingHelmut 2010-04-09 22:11
          • Meta-analysis vs. naïve pooling ElMaestro 2010-04-09 22:20
            • Meta-analysis vs. naïve pooling Helmut 2010-04-10 00:49
              • Meta-analysis vs. naïve pooling ElMaestro 2010-04-10 08:13
                • Yes, but... Helmut 2010-04-10 14:46
                  • Yes, but... ElMaestro 2010-04-11 11:44
                    • Yes, but... Helmut 2010-04-11 14:27
      • Meta-analysis alpha d_labes 2010-04-12 13:32
        • Meta-analysis alpha Helmut 2010-04-12 14:25
          • 2-Study Meta-analysis d_labes 2010-04-12 15:03
            • 2-Study Meta-analysis Helmut 2010-04-12 15:18
              • Anatomical miracle d_labes 2010-04-12 15:33
                • Anatomical miracle Helmut 2010-04-12 15:40