Bioequivalence and Bioavailability Forum

point estimate from 90% CI [General Statistics]

posted by yjlee168 – Kaohsiung, Taiwan, 2010-03-23 21:01 (5939 d 11:17 ago) – Posting: # 4965
Views: 4,958

Hi yuvrajkatkar,

❝ From your lectures, we can calculate point estimate from 90% confidence limits

❝

❝ Parameters Ratio 90% Confidence Interval

❝ AUC0-12 93.99 95.41 - 104.79

❝ AUC0-inf 89.48 93.37 – 107.10

❝ Cmax 96.57 95.01 – 105.23

❝

❝ Point Estimate= sqrt(Lower CI * Upper CI)

The equation is correct.

❝ Point estimte for Cmax= sqrt(95.01 * 105.23)= 99.99.

I guess that the value (96.57) showed in the Table could be the mean ratio (T/R) of Cmax, not the value of its point estimate.

—
All the best,
-- Yung-jin Lee
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Complete thread:

point estimate from 90% CI yuvrajkatkar 2010-03-23 11:14
- point estimate is not estimated d_labes 2010-03-23 11:39
- point estimate from 90% CIyjlee168 2010-03-23 20:01

point estimate from 90% CI [General Sta­tis­tics]

Complete thread:

point estimate from 90% CI [General Statistics]