Bioequivalence and Bioavailability Forum

Dear Ratnakar,

❝ Thanks for reply,

Your welcome

❝ It means that comparison of PK parameters of different parameters are compared irrespective of treatment given in the period (e.g. PK parameters of Test of 1 period are not compared with PK parameters of Test of period 2 or same for reference.

Yes, you are right.

❝ replicate study if there is in any two period will be indicated by p value of less than 0.05 and if p is more than 0.05 it means there is no significant difference between the values of all periods.

Yes, if p-value is less than 0.05 (for alpha=5%) then there is a significant difference between two or more periods and if more, then there is no significant difference between the values of all periods.


Regards,
Sinhmar