Bioequivalence and Bioavailability Forum

ANOVA of Model 1 [General Statistics]

posted by Helmut – Vienna, Austria, 2024-10-03 17:33 (232 d 07:19 ago) – Posting: # 24212
Views: 3,788

Hi BEQool,

❝ … what did you use as an error term (in the denominator) when testing group*treatment effect? MS Error (as for within-subject factors) or Subject(group×sequence) Error (as for between-subject factors)?

Here is the ANOVA of the first simulated study of our Scenario 1:

Response: log(Y) Df Sum Sq Mean Sq F value Pr(>F) group 1 0.171667589 0.1716675892 2.12908 0.151630 sequence 1 0.339810342 0.3398103421 4.21444 0.046057 * treatment 1 0.349206911 0.3492069106 4.33098 0.043277 * group:period 2 0.224598347 0.1122991734 1.39277 0.259120 group:sequence 1 0.053695040 0.0536950403 0.66594 0.418865 group:treatment 1 0.252244911 0.2522449107 3.12843 0.083870 . group:sequence:subject 44 5.173880238 0.1175881872 1.45837 0.107359 Residuals 44 3.547717653 0.0806299467 --- Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1

And then …

p.GxT[sim] <- anova(model1)[["group:treatment", "Pr(>F)"]]

… which is 0.083870. Did we screw up?

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Helmut Schütz

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Complete thread:

Group-by-Treatment Interaction: the final word? Helmut 2024-04-19 01:26
- Group-by-Treatment Interaction: FDA Helmut 2024-09-20 13:30
  - Group-by-Treatment Interaction: Rejoinder Helmut 2024-12-17 10:26
- Group-by-Treatment Interaction: the final word? BEQool 2024-10-03 15:09
  - ANOVA of Model 1Helmut 2024-10-03 15:33
    - ANOVA of Model 1 BEQool 2024-10-03 16:08
      - ANOVA of Model 1 Helmut 2024-10-04 10:11
        
        Between vs Within mittyri 2024-10-05 00:08
        
        Between vs Within BEQool 2024-10-06 20:06
        
        Treatment-by-Group in PROC MIXED and PROC GLM? mittyri 2024-10-06 22:00
        
        Treatment-by-Group in PROC MIXED and PROC GLM? BEQool 2024-10-07 10:27
        
        Treatment-by-Group in PROC MIXED and PROC GLM? mittyri 2024-10-07 13:11
        
        Treatment-by-Group in PROC MIXED and PROC GLM? BEQool 2024-10-14 11:01

ANOVA of Model 1 [General Sta­tis­tics]

Complete thread:

ANOVA of Model 1 [General Statistics]