Subject effect justification [General Sta­tis­tics]

posted by Dafni_C – Cyprus, 2024-01-17 11:00 (492 d 08:39 ago) – Posting: # 23829
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We have performed a bioequivalence study which passed the acceptance criteria. However there is a subject (sequence) effect for for ln-transformed pharmacokinetic parameters Cmax, AUC0-t and AUC0-∞. How this can be justified that doesn't affect the study results?:confused::confused:

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Pharmacokinetics may be simply defined as
what the body does to the drug,
as opposed to pharmacodynamics, which may be defined as
what the drug does to the body.    Leslie Z. Benet

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