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Registerhigher order crossover methodology [General Statistics]
❝ I just want to ask, whether you may want to give some more background information on the situation.
❝ Because I really was not able to think of a scenario, where considering only a part of the population based on the sequences could provide a benefit […]
Dear Steven, thanks for the feedback!
Here the first part of the 5-way crossover analysis (Part A- 3x3 analysis) would be under fasted conditions (Tablet formulation #1 vs. Tablet formulation #2 vs. Capsule formulation), and if BE is shown for either Tablet formulation vs. Capsule formulation, same subjects would complete in a 2x2 fashion under fed conditions (Tablet #1 or #2 [depending on BE result] vs. Capsule). In the final analysis, once all 5 sequences complete all 5 periods, fasted state vs. fed state to be compared for BE.
Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post #5! [Helmut]
Complete thread:
- higher order crossover methodology sweiner 2020-06-30 01:07
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- All dosed subjects have to be analyzed Helmut 2020-06-30 12:19
- All dosed subjects have to be analyzed sweiner 2020-06-30 17:08
- All dosed subjects have to be analyzed sedhosen 2021-03-16 08:30
- All dosed subjects have to be analyzed Helmut 2021-03-16 16:00
- higher order crossover methodology Relaxation 2020-06-30 14:10
- higher order crossover methodologysweiner 2020-06-30 17:10
- higher order crossover methodology ElMaestro 2020-06-30 18:17
- Fed (IBD) → fasting Helmut 2020-07-01 11:14
- Fed (IBD) → fasting sweiner 2020-07-07 03:00
- Fed (IBD) → fasting Helmut 2020-07-01 11:14
- higher order crossover methodology ElMaestro 2020-06-30 18:17
- higher order crossover methodologysweiner 2020-06-30 17:10
- All dosed subjects have to be analyzed Helmut 2020-06-30 12:19
Ing. Helmut Schütz