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RegisterSerum cortisol AUC [General Statistics]
Dear Yayati,
the AUC is the area under the curve and can therefore be estimated by any integration method you like regardless if you have serum cortisol or monthly income.
The most common one is the trapezoidal rule (which is based on linear interpolation) but you can also use log-linear interpolation, estimation of a polynomous function with arbitrary order (but less or equal to the number of time points) or some other function which make sense in your mind. Several textbooks give good explanations and examples on this toipc.
However, take care of any kind of pre-treatment adjustment, otherwise your AUC is biased.
Regards,
JPL
the AUC is the area under the curve and can therefore be estimated by any integration method you like regardless if you have serum cortisol or monthly income.
The most common one is the trapezoidal rule (which is based on linear interpolation) but you can also use log-linear interpolation, estimation of a polynomous function with arbitrary order (but less or equal to the number of time points) or some other function which make sense in your mind. Several textbooks give good explanations and examples on this toipc.
However, take care of any kind of pre-treatment adjustment, otherwise your AUC is biased.
Regards,
JPL
Complete thread:
- Serum cortisol AUC Yayati 2008-07-12 07:25
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Serum cortisol AUCJPL 2008-07-14 12:29
- Serum cortisol AUC Jaime_R 2008-07-14 15:34
- distribution of Serum cortisol AUC Yayati 2008-07-16 05:36
- Serum cortisol AUCJPL 2008-07-14 12:29
Ing. Helmut Schütz