Bioequivalence and Bioavailability Forum

...and a bonus question [General Sta­tis­tics]

posted by ElMaestro  – Denmark, 2018-02-09 12:32 (3037 d 09:35 ago) – Posting: # 18387
Views: 21,175

Hi Helmut,

I have a bonus question, although not about the correlation itself.

If I look at the location of your PE's on the horisontal axis (the AUC axis) then it looks to me like there are more points on the higher side of 1 than on the lower side.

Perhaps it is only a graphical artifact? Or something with the selection of studies plotted?

If not, then I wonder why that wold be so? I imagine you don't really have the answer but I am curious about any speculation from your side or from others. My head is already abuzz with stabilities and overages and much other weird stuff from the odd sock drawer of speculation.

If this is not an artifact then I am almost thinking this would be worth a publication (if it had no already been shown here).

Same might apply for the vertical axis, not sure. Perhaps I am only hallewcinating?

Complete thread:

• Power and type I adjustment for 222BE when several PK prams considered Louis52 2018-02-07 21:04 
  • Power and type I adjustment for 222BE when several PK prams considered ElMaestro 2018-02-07 22:37
  • Power of two combined TOST d_labes 2018-02-08 14:12
    • The mysterious ρ Helmut 2018-02-08 21:40
      • ρ ρ ρ your boat ElMaestro 2018-02-09 09:58
        • ρ ρ ρ your boat Helmut 2018-02-09 19:20
      • ...and a bonus questionElMaestro 2018-02-09 11:32
        • ...and a bonus question Helmut 2018-02-09 19:43
          • If u see a BEar don't forget to R oaρ Astea 2018-02-09 20:47
            • package install failed d_labes 2018-02-11 13:23
      • The mysterious ρ -between or within studies d_labes 2018-02-11 15:57
        • The mysterious ρ -between or within studies Helmut 2018-02-11 17:31
          • The mysterious ρ -between or within studies d_labes 2018-02-11 19:21
            • The mysterious ρ within studies Helmut 2018-02-11 22:44
              • The mysterious ρ within studies nobody 2018-02-12 09:08
        • The mysterious ρ -between or within studies Astea 2018-02-11 17:34
          • The mysterious ρ -between or within studies d_labes 2018-02-11 19:36
          • The mysterious ρ within studies Helmut 2018-02-11 22:48
  • Power and type I adjustment for 222BE when several PK prams considered ElMaestro 2018-02-11 18:43
    • Power and type I adjustment for 222BE when several PK prams considered nobody 2018-02-12 09:10
      • reminds me of something ElMaestro 2018-02-12 09:18
        • reminds me of something nobody 2018-02-12 09:38
          • Hammer to fall Astea 2018-02-12 18:37
            • Put the sickle to the corn Helmut 2018-02-13 01:37
              • Put the sickle to the corn Astea 2018-02-13 08:27
                • Put the sickle to the corn Helmut 2018-02-13 12:45
              • Put the sickle to the corn Relaxation 2018-02-13 10:37
                • multiple units, lag-times Helmut 2018-02-13 13:31