Bioequivalence and Bioavailability Forum

alpha TOST is not alpha 2-sided [General Statistics]

posted by d_labes – Berlin, Germany, 2017-03-28 17:12 (3364 d 08:17 ago) – Posting: # 17193
Views: 12,394

My Dear!

❝ (...) the p-value for "formulation" should also be significant at the 5% significance level assuming we work with alpha=5% and therefore 90% CI's.

❝ Alpha is alpha ...

I think here you err.
See this thread (evaluation without group effect):

p-value of treatment effect = 0.076998 (not significant at the 5% level)
90% CI = 90.76 ... 99.62% (doesn't contain 100%)

—
Regards,

Detlew

Complete thread:

Relationship between calculated 90% CI and sign. treatment effect in BE GM 2017-03-27 19:40
- 1–2α CI and TOST at α 0.05 Helmut 2017-03-27 23:47
  - 1–2α CI and TOST at α 0.05 GM 2017-03-28 06:50
    - 1–2α CI and TOST at α 0.05 DavidManteigas 2017-03-28 11:48
      - 1–2α CI and TOST at α 0.05 ElMaestro 2017-03-28 13:12
        
        alpha TOST is not alpha 2-sidedd_labes 2017-03-28 15:12
        
        Interesting! ElMaestro 2017-03-28 21:10
        
        Google has the answer d_labes 2017-03-29 08:20
        Interesting! DavidManteigas 2017-03-29 11:16
        
        Interesting! ElMaestro 2017-03-29 11:20
        
        Interesting! DavidManteigas 2017-03-29 12:28
        
        95% CI for a test on difference d_labes 2017-03-29 14:24
        Interesting! GM 2017-03-29 20:06
        
        Interesting! nobody 2017-03-30 08:24
      - Relationship between calculated 90% CI and sign. treatment effect in BE GM 2017-03-29 12:11
        
        Relationship between calculated 90% CI and sign. treatment effect in BE DavidManteigas 2017-03-29 12:30

alpha TOST is not alpha 2-sided [General Sta­tis­tics]

Complete thread:

alpha TOST is not alpha 2-sided [General Statistics]