baseline-corrected bioequivalence [General Sta­tis­tics]

posted by lizhao – US, 2014-11-06 23:19 (4241 d 11:54 ago) – Posting: # 13835
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If a PD endpoint is an endogenous hormone in human body. The PD metric is the change from baseline after taking the medicine. And it is also the PD metric is a concentration, so I should log-transform it.

Then should I use ln(post_treatment-baseline) as the bioequivalence metric?

Thanks

Edit: Please follow the Forum’s policy. [Helmut]

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