Sequence effects [General Sta­tis­tics]

posted by Imran  – Mumbai, 2007-12-13 11:05 (6763 d 06:34 ago) – Posting: # 1368
Views: 22,103

Dear HS and PK Friends

Please comment:
What will be significance of Sequence effect (P value less than 0.05) in the Primary variables (Cmax, AUCt and AUCinf) in the estimation of bioequivalence.

What justification or rational can be given if sequence effects are found in AUCs and the study is bioequivalent.

Thanks and Regards,

Dr.Imran Khan

Complete thread:

UA Flag
Activity
 Admin contact
23,654 posts in 4,992 threads, 1,570 registered users;
195 visitors (0 registered, 195 guests [including 23 identified bots]).
Forum time: 18:39 CEST (Europe/Vienna)

Actually, science starts to become interesting
only where it ends.    Justus von Liebig

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5