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Hi,
That has nothing to do with your situation. Since you ran a BE study with multiple groups, you need to demonstrate the absence of group effect. If there is a group effect then you would have to analyze the groups separately ⇒ This will elevate your CV (probably?) and reduce your power due to smaller sample size per group. I doubt that you will see a group effect if you ran the study groups in the same clinic and in different but within reasonable time frame.
See previous posts about group effect etc. There were some postings(I made some too) before...
John
❝ Some authors think that would apply only when the intra-subject variance is high and sample size is small.
That has nothing to do with your situation. Since you ran a BE study with multiple groups, you need to demonstrate the absence of group effect. If there is a group effect then you would have to analyze the groups separately ⇒ This will elevate your CV (probably?) and reduce your power due to smaller sample size per group. I doubt that you will see a group effect if you ran the study groups in the same clinic and in different but within reasonable time frame.
See previous posts about group effect etc. There were some postings(I made some too) before...
John
Complete thread:
- Doubt about analysis john john 2014-09-26 09:16
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Doubt about analysis ElMaestro 2014-09-26 10:05
- Doubt about analysis john john 2014-09-26 13:01
- What did you mean? ElMaestro 2014-09-26 13:13
- Doubt about analysisjag009 2014-10-01 21:04
- Doubt about analysis Ben 2014-10-05 10:57
- Doubt about analysis john john 2014-09-26 13:01
- Doubt about analysis ElMaestro 2014-09-26 10:05
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