Bioequivalence and Bioavailability Forum

Hello

❝ ...How on earth is table 11.4.8 to be interpreted?

The adhesion was evaluated at 9 time points during 24h for all subjects and the cummulative score was calculated, obtaining the CAS (Cummulative Adhesion Score) for each subject and treatment, which is the sum of all 9 scores.
We would have 9 evaluations for each period of each subject, each evaluation with a score from 0 to 4. Remember that the score will only increase from one time point to the next. These 9 scores would be cummulated to obtain the CAS. The values observed for CAS were 0 – 10 in this study. This table shows that, for instance, 22 of the 37 subjects had a CAS of 0 for the test treatment, meaning that the score for all the 9 time points of these subjects was 0.

But I just realised that I can't analyze the data without knowing the CAS for test and reference per subject. I was assuming that, for instance, the same subject who had a CAS of 10 for test had a CAS of 9 for reference, but I can't assume that. Very amateur mistake...