Bioequivalence and Bioavailability Forum

Dear Detlew,

❝ ❝ Does anybody know a reference supporting my – maybe too naïve – assumption?

❝

❝ What are the deeper reasons behind your question?

For years I’m trying to convince Pharsight to add it to the standard output of WinNonlin since un­trans­formed analysis is not uncommon for some PD-data. They cannot add something without a proper reference and the only one they could dig out so far was a little bit obscure.*
So they asked me. 

THX for your nice example!

---

• Mohsen MA. A Note on the Calculation of Intrasubject Coefficient of Variation in Bioequivalence Trails. J Bioanal Biomed. 2010;2(4):75–8. doi:10.4172/1948-593X.1000026.