Log in
RegisterPassing SD and Failing MD [General Statistics]
Hi HS
We have done a couple of studies for a molecule (BCS class II molecule, solubility lesser at higher pH, almost insoluble at pH 6 and above, MR pellets) .
In SD we got results like this
Cmax: 97% (87- 108)
AUC: 89 (82-96)
In MD, product failed in Cmin ss and AUCTss.
Exact values I do not remember, I need to look my old book for the same.
If you need details let me know, I will look for the same.
Regards
We have done a couple of studies for a molecule (BCS class II molecule, solubility lesser at higher pH, almost insoluble at pH 6 and above, MR pellets) .
In SD we got results like this
Cmax: 97% (87- 108)
AUC: 89 (82-96)
In MD, product failed in Cmin ss and AUCTss.
Exact values I do not remember, I need to look my old book for the same.
If you need details let me know, I will look for the same.
Regards
—
~A happy Soul~
~A happy Soul~
Complete thread:
- Simulation of data to predict Steady state cakhatri 2013-11-24 10:13
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Nonparametric superposition Helmut 2013-11-24 14:30
- Nonparametric superposition jag009 2013-11-24 23:13
- Nonlinear nightmare Helmut 2013-11-25 02:56
- Nonlinear nightmare jag009 2013-11-25 17:43
- Nonlinear nightmare Helmut 2013-11-26 14:32
- Nonlinear nightmare jag009 2013-11-26 16:00
- OT: Vienna Helmut 2013-11-26 16:27
- OT: Vienna jag009 2013-11-26 17:29
- OT: Vienna Helmut 2013-11-27 13:04
- OT: Vienna jag009 2013-11-26 17:29
- OT: Vienna Helmut 2013-11-26 16:27
- Nonlinear nightmare jag009 2013-11-26 16:00
- Nonlinear nightmare Helmut 2013-11-26 14:32
- Nonlinear nightmare jag009 2013-11-25 17:43
- Nonlinear nightmare Helmut 2013-11-25 02:56
- Conc at dosing interval jag009 2013-11-25 17:48
- Conc at dosing interval Helmut 2013-11-26 15:01
- Conc at dosing interval jag009 2013-11-26 17:31
- Conc at dosing interval Helmut 2013-11-27 13:10
- Conc at dosing interval jag009 2013-11-27 20:00
- Passing SD and Failing MDluvblooms 2013-11-28 09:19
- Passing SD and Failing MD Helmut 2013-11-29 17:29
- Passing SD and Failing MD luvblooms 2013-11-29 18:57
- Cτ predictive of Cmin Helmut 2013-11-30 17:25
- Passing SD and Failing MD luvblooms 2013-11-29 18:57
- Passing SD and Failing MD Helmut 2013-11-29 17:29
- Conc at dosing interval Helmut 2013-11-27 13:10
- Conc at dosing interval jag009 2013-11-26 17:31
- Conc at dosing interval Helmut 2013-11-26 15:01
- Nonparametric superposition jag009 2013-11-24 23:13
- Nonparametric superposition Helmut 2013-11-24 14:30
Ing. Helmut Schütz