Bioequivalence and Bioavailability Forum

SS, Unbalanced 3X3 crossover Design [General Statistics]

posted by ElMaestro – Denmark, 2013-06-06 14:06 (4758 d 00:14 ago) – Posting: # 10742
Views: 9,245

Hi again,

1. I do not have Excel. Try to see if you can invert matrices in a stable manner using inbuilt functions. If you can, then you have a way forward with the analytical solution above. Otherwise you might need to use the solver to optimise e^te, or to write some VBA scripts. You need to invest some energy of your own in this.

2. I don't know what you are trying to do so I don't feel able to tell if your design is correct. This looks like a pilot trial, in which case I would personally not bother too much with so many sequences stuff even though three treatments are involved.

3. The matrix equations above apply regardless of imbalance. Re carryover please see above.

—
Pass or fail!
ElMaestro

Complete thread:

Sum of squares for Unbalanced 3X3 crossover Design im.sagark 2013-06-06 09:16
- SS, Unbalanced 3X3 crossover Design ElMaestro 2013-06-06 11:13
  - SS, Unbalanced 3X3 crossover Design im.sagark 2013-06-06 11:20
    - SS, Unbalanced 3X3 crossover Design im.sagark 2013-06-06 11:31
      - SS, Unbalanced 3X3 crossover Design Dr_Dan 2013-06-06 12:21
        
        SS, Unbalanced 3X3 crossover Design im.sagark 2013-06-06 13:38
  - SS, Unbalanced 3X3 crossover Design im.sagark 2013-06-06 11:45
    - SS, Unbalanced 3X3 crossover DesignElMaestro 2013-06-06 12:06
      - SS, Unbalanced 3X3 crossover Design im.sagark 2013-06-06 12:27
        
        SS, Unbalanced 3X3 crossover Design ElMaestro 2013-06-06 12:55
        
        SS, Unbalanced 3X3 crossover Design im.sagark 2013-06-06 13:17
        
        SS, Unbalanced 3X3 crossover Design ElMaestro 2013-06-06 17:25
        
        SS, Unbalanced 3X3 crossover Design im.sagark 2013-06-07 05:54

SS, Unbalanced 3X3 crossover Design [General Sta­tis­tics]

Complete thread:

SS, Unbalanced 3X3 crossover Design [General Statistics]