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RegisterBE studies with Apple sauce [Study Performance]
posted by Helmut 
– Vienna, Austria, 2012-07-10 20:07 (5102 d 17:18 ago) – Posting: # 8919
Views: 6,866
Hi John!
Would be a surprise. pH of apple sauce is ~3.2–3.5; acidic but well above gastric conditions. Can’t imagine that the coating would be affected in the short time the pellets are sprinkled.
Very (very) unlikely, IMHO.
❝ Is it possible to fail a BE study on applesauce give that the fasting BE (non-applesauce) study is perfectly bioequivalent. […] Fed study is BE was well.
Would be a surprise. pH of apple sauce is ~3.2–3.5; acidic but well above gastric conditions. Can’t imagine that the coating would be affected in the short time the pellets are sprinkled.
❝ Just curious if the capsule shell itself would have an effect.
Very (very) unlikely, IMHO.
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Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz
The quality of responses received is directly proportional to the quality of the question asked. 🚮
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Complete thread:
- BE studies with Apple sauce jag009 2012-07-10 17:15
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- BE studies with Apple sauceHelmut 2012-07-10 18:07
- BE studies with Apple sauce jag009 2012-07-10 20:15
- BE studies with Apple sauceHelmut 2012-07-10 18:07
Ing. Helmut Schütz