Bioequivalence and Bioavailability Forum

Hi John!

❝ How do you deal with loss of urine due to spillage during collection? Example: When the subject discharges into the container, when clinic staff transfer the collected samples into a bigger bottle (24 hour pooling).

Spillage? Beware of shaky hands; get younger employees or use a funnel.

❝ Someone suggested that one should soak up the spillage with a towl and measure the volume spilled

How would one measure the volume then? Doable would be to weigh the towel (dry/wet) and calculate the volume based on measured density of the main sample. Is that really worth the efforts?