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More than 60 posts and still no reply?
Anyways, I read some more about it and found out that the reticuloendothelial system uptake of Iron sucrose is Dependant on molecular weight. Since our AUC values were on the higher side, I thought decreasing the Mol wt would help (since mol wt is inversely proportional to uptake). However, when I went thru documents, I found out that we had performed 2 studies; 1 in which test MW was much less than Reference and other with matching MW.
But the results of both are identical....
Totally Lost now.....
Dear member's please reply.
7060 – 7034 > 60?
[Helmut]
Anyways, I read some more about it and found out that the reticuloendothelial system uptake of Iron sucrose is Dependant on molecular weight. Since our AUC values were on the higher side, I thought decreasing the Mol wt would help (since mol wt is inversely proportional to uptake). However, when I went thru documents, I found out that we had performed 2 studies; 1 in which test MW was much less than Reference and other with matching MW.
But the results of both are identical....
Totally Lost now.....
Dear member's please reply.
7060 – 7034 > 60?
[Helmut]Complete thread:
- Iron Sucrose BE benovice 2011-05-31 13:33
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Iron Sucrose BEbenovice 2011-06-03 13:03
Ing. Helmut Schütz