Log in
RegisterAzithromycin suspension dosing [Study Performance]
Dr. Tarak,
Its a myth to assume that most of the antibiotics follow non-linear pharmacokinetics.
In this process it is understood that by whatever the mechanism saturation occurs, a small increment in dose will cause a large increase in blood concentration hence pk parameters like Cmax and AUC are bound to increase.
Please provide the literture citations for me to know that Azithromycin follow non-linear pharmacokinetics and by increasing the dose after saturation (or beyond linear range) there is no impact on AUC and Cmax.
Dr. Shiv
Edit: Full quote removed. [HS]
Its a myth to assume that most of the antibiotics follow non-linear pharmacokinetics.
In this process it is understood that by whatever the mechanism saturation occurs, a small increment in dose will cause a large increase in blood concentration hence pk parameters like Cmax and AUC are bound to increase.
Please provide the literture citations for me to know that Azithromycin follow non-linear pharmacokinetics and by increasing the dose after saturation (or beyond linear range) there is no impact on AUC and Cmax.
Dr. Shiv
Edit: Full quote removed. [HS]
Complete thread:
- Azithromycin suspension dosing gagandeep 2007-03-30 15:28
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Azithromycin suspension dosing Dr.Tarak Parikh 2007-04-05 06:38
- Azithromycin suspension dosing drshiv 2007-04-07 18:32
- Azithromycin suspension dosing Dr.Tarak Parikh 2007-04-09 13:08
- Azithromycin suspension dosingdrshiv 2007-04-12 14:46
- Azithromycin suspension dosing Dr.Tarak Parikh 2007-04-09 13:08
- Azithromycin suspension dosing drshiv 2007-04-07 18:32
- Azithromycin suspension dosing Dr.Tarak Parikh 2007-04-05 06:38
Ing. Helmut Schütz